�Scientific American magazine focussed on two University of Alabama at Birmingham (UAB) Comprehensive Cancer Center researchers in a news narrative on experimental next-generation antitumour therapies.
David T. Curiel, M.D., Ph.D., is a UAB professor of medicine and director of the human gene therapy division, and Ronald Alvarez, M.D., is a UAB professor of medicine and director of the gynaecological oncology division.
Both doctors ar featured in a Scientific American special cancer edition, and both served as co-authors on the report "Tumor-busting viruses." The editors chose Curiel and Alvarez because of their research into a field called viral cistron therapy, or virotherapy.
Virotherapy involves an experimental technique to target viruses to cancer cells while leaving intelligent cells untasted. The viruses are genetically engineered to kill tumor cells in different shipway. One way is by adopting the viruses' natural ability to invade and reproduce as a way to fork over target genes that throw tumor cells more susceptible to existing chemotherapies.
Curiel and Alvarez accept been testing this conception with a virus compound called adenovirus in women with perennial ovarian or other gynecological cancers. The clinical trial is silent in the early stages, yet the compound has shown anticancer effects that appear safe to near patients, Curiel said.
"We envision a substantial role for viruses - that is, therapeutic viruses - in 21st-century medicine," Curiel and Alvarez wrote in wrote in the story.
First proposed in the 1940s, virotherapy now relies heavily on adenoviruses, a cause of the usual cold that has been studied and altered extensively for aesculapian research. Adenoviruses have the ability to shuttle targeted segments of DNA into a neoplasm cell and make biochemical changes that minimize damage to healthy cells.
Source: Troy Goodman
University of Alabama at Birmingham
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Friday, 29 August 2008
Tuesday, 19 August 2008
Jared Leto responds to label lawsuit
30 Seconds To Mars singer Jared Leto has responded on his band�??s web site to a lawsuit brought against the group by Virgin/EMI to the tune of $30 million.
Opening with the news that his band possess no purpose of breaking up, Leto went on to discover the causa as �??ridiculously overblown�?? and says that the band are happily transcription their newfangled album in Los Angeles.
Of the case, Leto writes
�??As you crataegus laevigata have heard we are being sued by our former criminal record company for the ridiculously oversized, whole unrealistic and pretty ridiculous (but somewhat clever) amount of $30,000,000. Insane? Yea that's what we aforesaid too.�?�
Leto says California law states an artist or act cannot be bound to a record label deal for more than seven age, and that 30 Seconds To Mars get been in theirs for nine years.
�??It is a law that protects people from prolonged, unfair, career-spanning contracts. This law as well gave us the legal right to explore other possible opportunities.�?�
He then says it is because the band tried to extricate themselves from the contract that they ar being sued:
�??Yes we receive been sued by EMI. But NOT for weakness to deliver music or for 'quitting'. We get been sued by the corporation quite simply because roughly 45 days ago we exercised our legal right to terminate our old, prohibited of day of the month contract, which, according to the jurisprudence is aught and void.�?�
Leto then went on to talk about the fact that his band are still in debt to the label, after merchandising two billion albums.
�??If you think the fact that we throw sold in excess of 2 million records and have never been paid a penny is pretty unbelievable, well, so do we. And the fact that EMI informed us that not only aren't they leaving to pay us AT ALL simply that we are noneffervescent 1.4 million dollars in debt to them is even crazier. That the next record we make will be used to pay off that old supposed debt just now makes you start inquisitive what is going on. Shouldn't a record company be able to turn a profits from selling that many records? Or, at the very least, break even? We think so.�?�
--By our New York staff.
Find kayoed more around NME.
More info
Opening with the news that his band possess no purpose of breaking up, Leto went on to discover the causa as �??ridiculously overblown�?? and says that the band are happily transcription their newfangled album in Los Angeles.
Of the case, Leto writes
�??As you crataegus laevigata have heard we are being sued by our former criminal record company for the ridiculously oversized, whole unrealistic and pretty ridiculous (but somewhat clever) amount of $30,000,000. Insane? Yea that's what we aforesaid too.�?�
Leto says California law states an artist or act cannot be bound to a record label deal for more than seven age, and that 30 Seconds To Mars get been in theirs for nine years.
�??It is a law that protects people from prolonged, unfair, career-spanning contracts. This law as well gave us the legal right to explore other possible opportunities.�?�
He then says it is because the band tried to extricate themselves from the contract that they ar being sued:
�??Yes we receive been sued by EMI. But NOT for weakness to deliver music or for 'quitting'. We get been sued by the corporation quite simply because roughly 45 days ago we exercised our legal right to terminate our old, prohibited of day of the month contract, which, according to the jurisprudence is aught and void.�?�
Leto then went on to talk about the fact that his band are still in debt to the label, after merchandising two billion albums.
�??If you think the fact that we throw sold in excess of 2 million records and have never been paid a penny is pretty unbelievable, well, so do we. And the fact that EMI informed us that not only aren't they leaving to pay us AT ALL simply that we are noneffervescent 1.4 million dollars in debt to them is even crazier. That the next record we make will be used to pay off that old supposed debt just now makes you start inquisitive what is going on. Shouldn't a record company be able to turn a profits from selling that many records? Or, at the very least, break even? We think so.�?�
--By our New York staff.
Find kayoed more around NME.
More info
Saturday, 9 August 2008
Tuesday, 1 July 2008
DJ Gray
Artist: DJ Gray
Genre(s):
Other
Discography:
Second
Year: 2001
Tracks: 7
First
Year: 1999
Tracks: 5
Peter Andre
Monday, 30 June 2008
Blunt Tells Of Best Way To Pull At Glastonbury
James Blunt has given Gigwise some strong words of advice for anyone wanting to go on the pull at Glastonbury: “Get them drunk.”
The Beautiful singer (the song not the man) went on to defend his words by adding: “You’re always funnier and better looking when you’re drunk.”
Blunt is performing on the Pyramid stage today (June 28) and is critical of the way the media likes to quickly jump on people.
Talking of his own success and the hate that has surrounded him, he said he paid no attention to it because the fans speak for themselves.
“You know I’ve been on a world tour for 14 months and played to 3,5 and 20,000 people every night and they all come along and it doesn’t matter what sex or race or religion – they all leave with big smiles on their faces.
“There’s only a positive thing and reaction so it’s pretty hard to feel anything negative about it.”
He also commented on the media hype and stories surrounding tonights headliner, Jay-Z, by stating: “I think the British media have a wonderful knack of putting a negative spin on just about everything. I think maybe they should get out a bit more.”
We had time to quickly ask the ladies man if he had any advice from his numerous trips to Glastonbury. He said: “In the morning when you try to wake up, because you’re eyelids are quite thin aren’t they and always see light when it comes up, so its best to get a black marker pen and draw on the outside.”
Keep posted for more stories from the site as and when we get them.
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Paltrow rules out singing
Gwyneth Paltrow has ruled out ever having a music career, femalefirst.co.uk reports. The Iron Man actress� who showed off her vocal talents in the movie Duets � says despite being married to Coldplay front man Chris Martin, she will never try her luck as a singer. She said: �I have been approached to do records and stuff like that, which is very flattering. But I don�t really see myself as the type of person who could be put in a studio and be given a song that someone else wrote � with lyrics that someone else wrote � and then get all made up and have my hair blowing with a fan for a music video. That�s just not my style � I�m not into the packaged prefab music thing. I don�t really like Top 40 music � I don�t listen to it. First of all, I would only do it if I was going to be writing my own songs and I don�t even know if I could write a song because I had never tried.�
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Sunday, 29 June 2008
Are You a Saturday Night Fever Fan?
Send GMA your video tribute to the iconic '70s film, which came out 30 years ago
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